Lemtrada–Stopping the MS Attack?

Lemtrada is a once a year infusion that may slow or possibly stop the progression of multiple sclerosis. It is a once a year infusion, but the first year you receive infusions for five days in a row. Subsequent infusions are once a year but occur for three days in a row.

Insurance companies paint it as being for relapsing-remitting multiple sclerosis, MS, after two ms drugs have failed. That is because there is some risk to the infusions.

It reminds me of the procedure used that stopped my MS in its tracks in the early 2000s. I was given big bags of steroids for three days in a row, which dampens the immune system, while also physically making your body stronger. On the third day the infusion included Cytoxan which modifies your immune system.

Because your body is revved on steroids, the immune system modification occurs quickly. This was done every three to six months, depending upon how I was reacting. It worked. My MS symptoms remitted, and have continued to improve until the present.

It is my guess that the Lemtrada may be working similarly. There was a lot of risk with the procedure I went through, and there is risk with Lemtrada. I believe it may be risky because both procedures basically turn your immune system off temporarily, followed by the immune system being less hyperactive about attacking your nervous system.

Both procedures use steroids heavily, which dampens the immune system. I had a severe infection after one set of infusions that landed me in the hospital for a week which I recovered from.

I continued to improve using once a week Tysabri self-injections, which I did for almost ten years; however, there is a danger to using Tysabri. The danger is that you may activate a latent JV virus which then causes multiple myelomas in your brain. They have a test that indicated I was getting close to JV virus activation, so I fortunately was able to switch to the new 800 pound gorilla in the fight against multiple sclerosis, Ocrevus.

The first time you take Ocrevus, it is infusions given two days in a row. The infusions last for six months. Subsequent infusions occur every six months and are for one day, with the infusion taking three or four hours.

My health has steadily improved since my late fifties. At 66, I am in better health than I was in my thirties. I developed MS in 1991 right before the first effective medications for multiple sclerosis were developed. Ocrevus is the best one by far. Tysabri helped a lot, but I noticed that I was more likely to get a cold or the flu on Tysabri. That has not been the case with Ocrevus. Ocrevus is for both primary progressive multiple sclerosis and relapsing remitting MS.

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Surgery with your eye muscles bilaterally to heal double vision from multiple sclerosis MS

Looking at Life Straight-on

I recently had surgery on my eyes for double vision which I trace back to probably being caused by MS. Visual symptoms were the first thing I noticed in my late twenties which I think was a precursor to being diagnosed with primary progressive multiple sclerosis at age 36.

Right after the surgery, the double vision changed. Over the course of three weeks, it merged into unitary singular vision. They do not operate on the eyes themselves. They operate on the small muscles controlling those movements. They ” tighten the cables” leading to your eyes if you will. Anyway, you are put under anesthesia and released the same day so it is outpatient surgery.

I have excessive skin on my eyelids which I think contributed to the double vision (if you put pressure on the outside of your eye with a finger, it distorts your vision which is a similar effect). Surgery can remove the excessive skin safely, so I think I will do it. Anyway, for 2019, “the eyes (ayes) have it.”

For the next few days, Amazon is giving the book away free at https://www.amazon.com/dp/B07D7JBZ5L/ref=cm_sw_r_fa_awdo_t1_.pDiBbVDAK0S4

70% of MS patients regain functioning with extreme treatment–but you might die

Rebooting the immune system

A radical new treatment for multiple sclerosis is on the way. Researchers noticed that a leukemia treatment that works also practically cured MS patients who had both leukemia and multiple sclerosis.

Seventeen of the sample of 24, which is 70% of the people who used this treatment, had marked improvement in their MS symptoms (such as being able to return to work). One of the 24 MS patients died.

First bone marrow cells are extracted from the patient. Then all the immune cells in the patient are killed with toxic chemotherapy. The bone marrow sample is then purged of cancerous cells. The final step is the bone marrow sample is injected back into the patient to reboot the immune system of the MS sufferer.

For more information about this treatment, go to https://www.newscientist.com/article/2093280-extreme-cure-for-ms-reboots-immune-system-but-can-be-fatal/